Gene interactions and pathways from curated databases and text-mining

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BMP2 — TNFRSF11B

Text-mined interactions from Literome

Wan et al., J Biol Chem 2001 : In this study, we have characterized the transcription mechanism of BMP induced OPG gene expression ... Collectively, our data indicate that Hox sites mediate both OPG promoter construct activity and endogenous OPG gene expression in response to BMP stimulation
Fujita et al., Molecular cancer 2007 (Plasmacytoma) : Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2 induced osteoblast differentiation and expression of OPG , RANKL and M-CSF
Susperregui et al., J Cell Physiol 2008 : Similarly, PTHrP did not significantly modify the BMP regulated expression of RANKL or OPG , cytokines involved in osteoclastogenesis
Sato et al., Genes Cells 2009 : Bone morphogenetic protein-2 enhances Wnt/beta-catenin signaling induced osteoprotegerin expression ... BMP-2 enhanced Wnt/beta-catenin dependent transcriptional activation of the OPG promoter
Zhou et al., Nan Fang Yi Ke Da Xue Xue Bao 2013 : Adenovirus mediated overexpression of BMP-2 and BMP-3, however, promoted osteogenesis of NP cells and significantly increased the expression of osteocalcin mRNA ; the overexpression of BMP-2 , but not BMP-3, enhanced the mRNA expressions of osteoprotegerin and osteopontin
Hofbauer et al., Biochem Biophys Res Commun 1998 : Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2 , and cytokines ... Interleukin (IL)-1beta ( 5 x 10 ( -9 ) M ), tumor necrosis factor (TNF)-alpha ( 9 x 10 ( -9 ) M ), and bone morphogenetic protein (BMP)-2 ( 100 ng/ml ) also increased OPG mRNA levels in hFOB cells by 4-, 6-, and 4-fold, respectively