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ARNT — SETD2

Text-mined interactions from Literome

Chilov et al., J Cell Sci 1999 (Anoxia...) : As shown by immunofluorescence, HIF-1alpha accumulation in the nucleus of hypoxic cells was independent of the presence of ARNT , suggesting that nuclear translocation is intrinsic to HIF-1alpha
Chun et al., Biochem Biophys Res Commun 2000 : In this study, we found that zinc induced the accumulation and nuclear translocation of hypoxia-inducible factor (HIF)-1alpha but inhibited the nuclear translocation of HIF-1beta , which inactivated HIF-1 and suppressed EPO mRNA induction in hypoxic cells
Gassmann et al., Adv Exp Med Biol 2000 (Anoxia) : As shown by immunofluorescence, HIF-1 alpha accumulation in the nucleus of hypoxic cells did not require ARNT , demonstrating that nuclear translocation is intrinsic to HIF-1 alpha
Lee et al., Nucleic Acids Res 2004 (Anoxia) : Moreover, HIF-1alpha417 promoted the nuclear translocation of ARNT , and conversely ARNT stabilized HIF-1alpha417
Nguyen-Khac et al., Oncogene 2006 : Interestingly, stable expression of the TEL-ARNT in 32Dcl3 subclones resulted in impaired HIF1 mediated transcriptional response and inhibition of differentiation enhancement in hypoxic conditions
Choi et al., Mol Pharmacol 2006 (Neoplasms) : However, although ARNT is also required for HIF-1 activity, ARNT has been disregarded as a therapeutic target