Gene interactions and pathways from curated databases and text-mining

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CSH2 — INS

Text-mined interactions from Literome

Ren et al., Endocrinology 1991 (Choriocarcinoma) : Recent studies have shown that insulin regulates placental lactogen , progesterone, and estrogen production from human trophoblast cells
Leturque et al., Diabete Metab 1989 : Effects of placental lactogen and progesterone on insulin stimulated glucose metabolism in rat muscles in vitro
Sorenson et al., Pancreas 1987 : In order to determine the effect of lactogen on insulin secretion and junctional coupling among islet beta cells, ovine prolactin ( oPRL ) was infused by Alzet minipumps into female rats for 4 days
Bhaumick et al., Biochem Biophys Res Commun 1987 : The effects of insulin-like growth factor-I and insulin on placental lactogen production by human term placental explants ... The effects of insulin-like growth factor (IGF)-I and insulin on placental lactogen production ( hPL ) by term human placental explants were studied
Hochberg et al., J Clin Endocrinol Metab 1983 : Insulin regulates placental lactogen and estradiol secretion by cultured human term trophoblast ... We conclude that insulin regulates secretion of estradiol and placental lactogen by cultured human term trophoblast
Lochnan et al., Mol Cell Endocrinol 1995 : Human placental lactogen and bovine PRL could also induce a greater than 10-fold induction, whereas insulin did not significantly stimulate the beta-casein promoter
Kawai et al., J Reprod Fertil 1997 : The present study investigated the effect of rat placental lactogen-II ( rPL-II ) on insulin secretion and B-cell proliferation of the maternal islets during the last half of pregnancy in rats using a homologous system
McLeod et al., J Anim Sci 1997 : The CSH increased ( P < .05 ) PDV release of beta-hydroxybutyrate and insulin and increased ( P = .09, CSH alone vs control ) net release of glucose in the absence of exogenous SRIF ... Net total splanchnic alpha-amino N release and oxygen consumption were decreased ( P < .10 ) with exogenous SRIF, but CSH increased ( P < .05 ) insulin release and oxygen consumption
Weinhaus et al., Diabetes 1998 : The similar increases in insulin secretion and cAMP concentration suggest that changes in cAMP metabolism are involved in lactogen induced upregulation of insulin secretion