Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Klein et al., Acad Med 2002 (Diabetes Mellitus, Type 2) : Other diabetes related topics include wound healing ( epithelium ), basement membrane thickening ( connective tissue ), insulin regulation of muscle metabolism, diabetic neuropathy ( neurohistology ), platelet adhesiveness, glycation and HbA1c ( blood ), osteoporosis and Charcot joints ( skeletal system ), autoimmune mechanisms ( cellular immunology ), atherosclerosis and high blood pressure ( blood vessels ), diabetic nephropathy ( renal ), altered hepatic and gastrointestinal function, impotence ( male reproductive system ), and a comparison of type I and type II diabetes ( endocrine system )
Groop et al., Diabetes Care 1992 (Diabetes Mellitus, Type 2) : Morning and bedtime NPH insulin resulted in equal reduction of HbA1 ( from 13.5 +/- 0.3 to 9.4 +/- 0.1 and 9.6 +/- 0.2 %, respectively ) and mean self monitored blood glucose ( 9.2 +/- 0.5 vs. 10.1 +/- 0.4 mM )
Hartemann-Heurtier et al., Diabetes Res Clin Pract 2009 (Body Weight...) : Insulin and pioglitazone resulted in a significant decrease in HbA1c ( -1.6 % and -1.2 %, respectively ) and a significant increase in total body fat mass ( 1+/-2.3 and 3.3+/-2.7 kg, respectively )
Levitt Katz et al., J Pediatr 2011 (Diabetes Mellitus, Type 2) : At baseline, Mann Whitney tests demonstrated that the diabetic ketoacidosis group had higher HbA1c ( P = .002 ), required more insulin ( P = .036 ), and had lower C-peptide ( P = .003 ) than the NA group
Yamazaki et al., Journal of toxicologic pathology 2009 : By 9 and 12 weeks of age, the plasma insulin levels had decreased to mid levels and HbA1c had increased to mid to high levels ; histopathological examination at this time revealed two types of islets coexisting, enlarged circular islets and small irregular shaped islets
Fredheim et al., Diabetologia 2013 (Diabetes Mellitus, Type 1...) : DKA ( moderate and severe ) was associated with increased HbA1c ( % ) levels ( 0.24 ; 95 % CI 0.11, 0.36 ; p = 0.0003 ) and increased insulin dose adjusted HbA1c ( IDAA1c, 0.51 ; 95 % CI 0.31, 0.70 ; p < 0.0001 ) during follow-up, after adjustment for covariates
Burden et al., Ann Intern Med 2013 : CONCLUSIONS In patients with type 1 diabetes mellitus, real-time continuous glucose monitoring ( rt-CGM ) reduces glycated hemoglobin ( HbA1c ) more than self monitoring of blood glucose ( SMBG ), and rt-CGM plus rapid acting analogue based continuous subcutaneous insulin infusion reduces HbA1c more than multiple daily injections plus SMBG