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BAX — PCBD1
Text-mined interactions from Literome
Levine et al., J Biol Chem 2001
:
Here we show that
Bax induced
PCD of yeast was suppressed by transformation with a vesicle associated membrane protein from Arabidopsis ( AtVAMP ), which was isolated by screening a cDNA expression library against sugar induced cell death in yeast ... AtVAMP expression blocked
Bax induced
PCD downstream of oxidative burst
Sun et al., J Neurosci 2004
:
Several markers for apoptosis failed to reveal cell death in Bax-deficient mice, and this, together with a progressive increase in neuron number in the DG of the Bax knock-out, indicates that
Bax is
critical for the
PCD of adult generated hippocampal neurons ... Whereas the proliferation of neural progenitor cells was not altered in the Bax-knock-out, there was an accumulation of doublecortin, calretinin+, and neuronal-specific nuclear protein+ postmitotic neurons, suggesting that
Bax mediated
PCD of adult generated neurons takes place during an early phase of differentiation
Yang et al., Plant Physiol 2007
:
Overexpression of BAP1 or BAP2 with their partner BON1 inhibits
PCD induced by pathogens, the proapoptotic gene
BAX , and superoxide generating paraquat in Arabidopsis or Nicotiana benthamiana
Kim et al., Eur J Neurosci 2009
(Synaptic Transmission) :
These results suggest that the elimination of excess DG neurons via
Bax dependent
PCD in the adult brain is required for the normal organization and function of the hippocampus