Gene interactions and pathways from curated databases and text-mining

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BAX — PCBD1

Text-mined interactions from Literome

Levine et al., J Biol Chem 2001 : Here we show that Bax induced PCD of yeast was suppressed by transformation with a vesicle associated membrane protein from Arabidopsis ( AtVAMP ), which was isolated by screening a cDNA expression library against sugar induced cell death in yeast ... AtVAMP expression blocked Bax induced PCD downstream of oxidative burst
Sun et al., J Neurosci 2004 : Several markers for apoptosis failed to reveal cell death in Bax-deficient mice, and this, together with a progressive increase in neuron number in the DG of the Bax knock-out, indicates that Bax is critical for the PCD of adult generated hippocampal neurons ... Whereas the proliferation of neural progenitor cells was not altered in the Bax-knock-out, there was an accumulation of doublecortin, calretinin+, and neuronal-specific nuclear protein+ postmitotic neurons, suggesting that Bax mediated PCD of adult generated neurons takes place during an early phase of differentiation
Yang et al., Plant Physiol 2007 : Overexpression of BAP1 or BAP2 with their partner BON1 inhibits PCD induced by pathogens, the proapoptotic gene BAX , and superoxide generating paraquat in Arabidopsis or Nicotiana benthamiana
Kim et al., Eur J Neurosci 2009 (Synaptic Transmission) : These results suggest that the elimination of excess DG neurons via Bax dependent PCD in the adult brain is required for the normal organization and function of the hippocampus