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IRF6 — KCNMA1

Text-mined interactions from Literome

Müller et al., J Endotoxin Res 2003 : MaxiK can be activated by agonistically active LPS , and activation can be completely inhibited by LPS antagonists ( e.g. synthetic compound 406 ) and by anti-CD14 antibodies ... Thus, since cells lacking TLR4 on their surface can also not be activated to produce cytokines, these data allow the conclusion that TLR4 and MaxiK are both essential for activation by LPS and may form a co-operative signaling complex
Hoang et al., Br J Pharmacol 1998 (Ion Channel Gating) : N ( omega ) -nitro-D-arginine ( 50 microM ), a poor inhibitor of NOS in in vitro assays, had no effect on BK channel activation by LPS