◀ Back to CASP3

CASP3 — PPARA

Text-mined interactions from Literome

Billiet et al., J Mol Biol 2008 : Finally, PPARalpha activation reduced the lidocaine induced caspase-3 activity and apoptosis, which might be due to the VDUP-1 mediated regulation of the Bax/Bcl-2 ratio
Chen et al., American journal of physiology. Renal physiology 2009 (Reperfusion Injury) : Overexpression of prostacyclin using an adenovirus could also induce PPAR-alpha translocation from the cytosol into the nucleus to inhibit caspase-3 activation
He et al., Zhongguo Fei Ai Za Zhi 2006 : Activated PPAR-? can increase caspase-3 activity to induce apoptosis of cells
Wang et al., Acta Diabetol 2013 : Additionally, the enhancement of PPAR? expression by treatment with TZDs inhibited the expression of caspase 3 in IL-1ß/IFN-? induced NIT-cells
Wang et al., Oncogene 2012 (Colorectal Neoplasms) : More importantly, the opposing effects of PPARd and PPAR? in regulating programmed cell death are mediated by survivin and caspase-3
Yuan et al., Cancer prevention research (Philadelphia, Pa.) 2012 (Genetic Predisposition to Disease) : Here, we report that the absence of Sca-1 in the mammary gland resulted in higher levels of PPAR? and PTEN, and a reduction of pSer84PPAR?, pERK1/2, and PPARd ... Reduction of Sca-1 expression in mammary tumor cells by RNA interference resulted in a phenotype similar to the Sca-1 deficient mammary gland, as evidenced by increased PPAR? expression and transcriptional activity, resulting in part from a lesser susceptibility to proteasomal degradation
Qiu et al., Food Chem Toxicol 2013 (MAP Kinase Signaling System...) : Caspase-3 was also activated and PPAR-? protein expression increased in drug induced apoptosis