Gene interactions and pathways from curated databases and text-mining

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HSPB1 — PRKCA

Text-mined interactions from Literome

Patil et al., Am J Physiol Gastrointest Liver Physiol 2004 : These data suggest that there is a direct association of translocated calponin and PKC-alpha in the membrane and a role for the complex calponin-PKC-alpha-HSP27 , in contraction of colonic smooth muscle cells
Patil et al., Am J Physiol Gastrointest Liver Physiol 2006 : RhoA- and PKC-alpha mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells ... Acetylcholine induced 1 ) sustained phosphorylation of PKC-alpha , CPI-17, and MYPT; 2 ) an increase in the association of phospho-MYPT with HSP27 in the particulate fraction ; 3 ) a decrease in myosin phosphatase activity ( 66.21+/-3.52 and 42.19+/-3.85 % nM/ml lysate at 30 s and 4 min ) ; and 4 ) an increase in PKC activity ( 298.12+/-46.60 % and 290.59+/-22.07 % at 30 s and 4 min )