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IRF6 — RAF1

Text-mined interactions from Literome

Tominaga et al., Biochim Biophys Acta 1999 : Activation of Raf-1 , located in the upstream portion of ERK cascades, was also suppressed by LPS-tolerance induction
Monick et al., J Immunol 2000 : LPS did not activate Raf-1 , the classic activator of MEK
Liu et al., Mol Cell Biol Res Commun 2001 (MAP Kinase Signaling System) : Despite considerable degrees of overlap, LPS signaling is not affected by Raf-1
Tsai et al., Inflammation 2008 : Furthermore, ATRA suppressed the expression of LPS stimulated c-Raf , MKK1/2 and ERK expression of THP-1 cells
Büscher et al., Mol Cell Biol 1995 : Therefore, CSF-1 and LPS target the MAPK network by two alternative pathways, both of which induce Raf-1 activation
Guthridge et al., Mol Cell Biol 1997 : An in vitro Raf-1 kinase assay, however, failed to detect LPS induced Raf-1 kinase activity in RAW 264.7 cells, suggesting that in RAW 264.7 cells, Raf-1 kinase is not an activating component of the LPS signaling pathway regulating MAPK activity or sIL-1Ra promoter activity