Gene interactions and pathways from curated databases and text-mining

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E2F1 — MCM5

Text-mined interactions from Literome

Ohtani et al., Oncogene 1999 (Teratocarcinoma) : Our results demonstrated that the growth regulated expression of mammalian MCM5 and MCM6 genes, and presumably other MCM members, is primarily regulated by E2F through binding to multiple E2F sites in the promoters
Bruemmer et al., Exp Cell Res 2003 (Coronary Restenosis...) : In combination, these data demonstrate that the ERK/MAPK signal transduction pathway plays a central role in regulating E2F dependent MCM expression and DNA replication in VSMC