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Text-mined interactions from Literome
Noguchi et al., Inflammation 1999
:
IL-4 and
IFN-gamma suppressed PGE2 production by IL-1beta stimulated PDL fibroblasts, but
COX activity enhanced by IL-1beta treatment was significantly
inhibited by IL-4, not by IFN-gamma
Hayashi et al., Cytokine 2000
:
The regulatory
effects of
interferon (IFN)-gamma and IL-4 on IL-1beta induced
COX , PLA(2)isoforms expression and terminal delayed PGE ( 2 ) generation were examined in three types of human fibroblasts
Murakami et al., Carcinogenesis 2002
(Adenocarcinoma...) :
The combined lipopolysaccharide- and
interferon-gamma stimulated protein expressions of inducible nitric oxide synthase and
cyclooxygenase (COX)-2 , together with the release of tumor necrosis factor-alpha, in RAW 264.7 mouse macrophages were also markedly diminished
Yu et al., Biochim Biophys Acta 2002
:
Reporter assays also demonstrated reduced
IFN gamma stimulated transcriptional activity of the iNOS and
COX2 promoters by CLA
Shibata et al., J Neurochem 2003
:
SB203580 also suppressed expression of iNOS and
cyclooxygenase-2 (COX-2) induced by
IFN-gamma/LPS
Han et al., Life Sci 2004
:
The studies showed that ABL not only inhibited LPS/IFN-gamma mediated nitric oxide ( NO ) production and inducible nitric synthase ( iNOS ) expression, but also decreased
LPS/IFN-gamma induced prostaglandin E2 ( PGE2 ) production and
cyclo-oxygenase-2 (COX-2) expression in a concentration dependent manner
Hanna et al., Am J Reprod Immunol 2004
(Obstetric Labor, Premature) :
The aim of this study was to evaluate the
effects of
interferon (IFN)-gamma on the expression of
Cyclooxygenase (COX)-2 and production of prostaglandin E ( 2 ) ( PGE ( 2 ) ) in the human placenta from term and preterm labor deliveries
Vila-del Sol et al., J Immunol 2005
:
IFN-gamma induces
cyclooxygenase (COX)-2 expression and PG production in mouse macrophage cells
Caruso et al., Endocrinology 2007
(Inflammation) :
alpha-MSH ( 5 microm ) reduced the nitric oxide production and the expression of inducible nitric oxide synthase (iNOS) induced by bacterial lipopolysaccharide ( LPS, 1 microg/ml ) plus interferon-gamma ( IFN-gamma, 50 ng/ml ) in cultured astrocytes after 24 h. alpha-MSH also attenuated the stimulatory
effect of
LPS/IFN-gamma on prostaglandin E ( 2 ) release and
cyclooxygenase-2 (COX-2) expression
Martin et al., Kidney Int 1994
:
Interferon gamma , which did not
induce prostaglandin synthesis or influence
COX mRNA expression, augmented the expression of MHC antigens in RMC
Pang et al., Br J Pharmacol 1997
:
2. We studied the
effects of IL-1 beta, TNF alpha and
IFN gamma on the induction of two isoforms of cyclo-oxygenase and its relation to prostaglandin E2 ( PGE2 ) release and
COX activity ( reflected by PGE2 synthesis from exogenous arachidonic acid ) in human cultured airway smooth muscle cells
Endo et al., Am J Respir Cell Mol Biol 1998
:
Lipopolysaccharide (LPS) stimulated PGE2 synthesis and
COX activity were suppressed significantly by IL-4, but were not
affected significantly by IL-10, IL-13, or
IFN-gamma