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IL21 — MMP13
Text-mined interactions from Literome
Meisser et al., Mol Hum Reprod 1999
:
The aim of this study was to determine the
effects of tumour necrosis factor alpha (TNF),
interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of
matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Wahlgren et al., J Pathol 2001
(Bone Diseases...) :
Phorbol-12-myristate-13-acetate,
interleukin-6 , and tumour necrosis factor-alpha and heparin with the tumour promoter or cytokines potently
enhanced ( up to nine-fold )
MMP-8 and -13 expression by the RPMI 8226 myeloma cell line, as evidenced by western blotting and semi-quantitative reverse transcriptase-polymerase chain reaction
Himeno et al., J Bone Miner Res 2002
(Ossification, Heterotopic) :
In primary culture of Cbfa1-/- chondrocytes, transforming growth factor (TGF) beta1, platelet derived growth factor ( PDGF ),
interleukin (IL)-1beta , and thyroid hormone ( T3 )
induced osteopontin and
MMP-13 expression
Sun et al., Connect Tissue Res 2003
(Arthritis, Rheumatoid) :
Furthermore, the
induction of the
MMP expression and activities by
interleukin-1 was suppressed by the oscillatory shear
Monteleone et al., Gut 2006
(Colitis, Ulcerative...) :
To investigate whether
IL21 controls
MMP production by intestinal fibroblasts ...
IL21 enhances fibroblast production of MMP-1,
MMP-2 , MMP-3 and MMP-9, but not tissue inhibitors of MMP-1 and MMP-2 ...
IL21 enhances
MMP secretion without affecting gene transcription and protein synthesis ... These results suggest that fibroblasts are a potential target of IL21 in the gut and that
IL21 controls
MMP secretion by fibroblasts
Im et al., J Biol Chem 2007
:
bFGF stimulation of
MMP-13 was
mediated at the transcriptional level and, at least in part, by stimulation of
interleukin-1 production
Caruso et al., J Immunol 2007
(Gastritis...) :
In this study, we have examined the role of the T cell cytokine IL-21 in Hp-infected gastric mucosa and evaluated whether
IL-21 regulates
MMP production by gastric epithelial cells
Ahmad et al., Cell Signal 2007
(MAP Kinase Signaling System) :
MyD88, IRAK1 and TRAF6 knockdown in human chondrocytes inhibits
interleukin-1 induced
matrix metalloproteinase-13 gene expression and promoter activity by impairing MAP kinase activation
Ito et al., Ultrasound Med Biol 2012
:
Low-intensity pulsed ultrasound inhibits messenger RNA expression of
matrix metalloproteinase-13 induced by
interleukin-1ß in chondrocytes in an intensity dependent manner
Culley et al., Arthritis Rheum 2013
(Disease Models, Animal...) :
Knockdown of each class I HDAC diminished
interleukin-1 induced
MMP13 expression