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MLXIPL — PPP2R1A
Text-mined interactions from Literome
Dentin et al., J Hepatol 2012
:
In contrast to the current proposed model, our study reports that
PP2A activity is dispensable for ChREBP activation in response to glucose and that dephosphorylation on Ser-196 is not
sufficient to promote
ChREBP nuclear translocation in the absence of a rise in glucose metabolism
Liangpunsakul et al., J Investig Med 2013
:
The effect of ethanol on
ChREBP was attenuated in the presence of okadaic acid, an
inhibitor of
PP2A ... The effects of ethanol on AMPK and
PP2A may
result in activation of
ChREBP , providing another potential mechanism for ethanol induced hepatic steatosis