Gene interactions and pathways from curated databases and text-mining

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IL8 — IRS1

Text-mined interactions from Literome

Kim et al., J Biol Chem 2005 (Inflammation) : In addition, using a phospho-specific antibody against IRS-1 phosphorylated at Ser ( 24 ), we found that interleukin-1 or TNF-alpha treatment of Fao cells stimulated increased phosphorylation of endogenous IRS-1 at Ser ( 24 )
Britschgi et al., Cancer Cell 2012 (Breast Neoplasms...) : Mechanistically, PI3K/mTOR inhibition increased IRS1 dependent activation of JAK2/STAT5 and secretion of IL-8 in several cell lines and primary breast tumors