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IL8 — IRS1
Text-mined interactions from Literome
Kim et al., J Biol Chem 2005
(Inflammation) :
In addition, using a phospho-specific antibody against IRS-1 phosphorylated at Ser ( 24 ), we found that
interleukin-1 or TNF-alpha treatment of Fao cells
stimulated increased phosphorylation of endogenous
IRS-1 at Ser ( 24 )
Britschgi et al., Cancer Cell 2012
(Breast Neoplasms...) :
Mechanistically, PI3K/mTOR inhibition increased
IRS1 dependent activation of JAK2/STAT5 and secretion of
IL-8 in several cell lines and primary breast tumors