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IL17A — PI3

Text-mined interactions from Literome

Park et al., Eur Respir J 2010 (Asthma) : Recent findings have indicated that PI3Ks also regulate the expression of interleukin (IL)-17 , which has been recognised as an important cytokine involved in airway inflammation ... In the present study, we investigated a role of PI3Kd in the regulation of IL-17 expression in allergic airway disease using a murine model of asthma
Roller et al., J Immunol 2012 (Dermatitis...) : We also show that PI3Kd and PI3K? inhibitors reduced IFN-? production by human TCR?d T cells and IL-17 and IFN-? production by PBMCs from psoriatic or healthy donors
Liu et al., Autophagy 2013 (Pulmonary Fibrosis) : In response to IL17A stimulation, PI3K was activated and resulted in phosphorylation of GSK3B at Ser9, which subsequently attenuated the interaction of GSK3B with BCL2