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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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CCL2 — NUP43

Text-mined interactions from Literome

Schecter et al., J Leukoc Biol 2004 : MCP-1 induces a time- and concentration dependent phosphorylation of the mitogen activated protein kinases p42/44
Hirata Terra et al., Anal Biochem 2004 : Here, we describe an alternative bioassay based on MCP-1 induced phosphorylation of the mitogen activated protein kinases ( MAPK ) p44 ( ERK1 ) and p42 ( ERK2 )
Fasshauer et al., Biochem Biophys Res Commun 2004 : Studies using pharmacological inhibitors suggested that the positive effects of GH and IL-6 on MCP-1 synthesis are at least in part mediated by janus kinase 2 and p44/42 mitogen activated protein kinase
Fang et al., J Biol Chem 2012 (Breast Neoplasms...) : RNA interference of CCR2 expression in breast cancer cells significantly inhibited CCL2 induced migration, survival, and phosphorylation of Smad3 and p42/44MAPK proteins ... These data indicate that Smad3 signaling through MEK-p42/44MAPK regulates CCL2 induced cell motility and survival, whereas CCL2 induction of MEK-p42/44MAPK signaling independent of Smad3 functions as an alternative mechanism for cell survival