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GPI — SERPINC1

Text-mined interactions from Literome

Salvatierra et al., Circulation 2001 (Reperfusion Injury) : The beneficial effect of AT III was not observed when dogs received indomethacin to prevent the stimulation of PGI ( 2 ) release by AT III
Hayashi et al., Thromb Res 1991 : ATIII at 40 mInh.U/ml and more significantly inhibited thrombin induced PGI2 production by A10 cells, but HCII at the same doses did only slightly
Horie et al., Thromb Res 1990 : Antithrombin III (ATIII) induced a marked increase in prostacyclin ( PGI2 ) release from cultured human umbilical vein endothelial cells ( HUVEC ) after incubation for more than 2 hr and the induction continued for 8 hr, while thrombin induced the increase within 10 min. ATIII dependent production of PGI2 was abolished by addition of heparin, but pretreatment of HUVEC with polyclonal antibody against thrombomodulin could not prevent the PGI2 productions by ATIII and thrombin ... ATIII dependent PGI2 production was significantly inhibited by pretreatment of HUVEC with beta-D-xylosides or heparitinase, though neither pretreatment affected thrombin induced PGI2 production ... ATIII dependent PGI2 production was completely abolished ... The ATIII induced PGI2 production is very different from that induced by thrombin