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IGF1 — POLDIP2
Text-mined interactions from Literome
Kooijman et al., Cell Signal 2003
:
We also show that IGF-I stimulates the activation of ERK1 and ERK2, but we could not detect any
effect of
IGF-I on the phosphorylation of
p38 , JNK ( p46 ) or JNK ( p54 )
Wilkins et al., J Neurochem 2005
(Demyelinating Diseases...) :
OCM and
IGF-1 ( but not GDNF )
reduced p38 activation in NO-exposed cortical neurones
Guo et al., Biochim Biophys Acta 2008
:
This early PM was neither prevented by
IGF-I ,
inhibitors of
p38 , ERK1/2, or PPARgamma nor significantly accelerated by LPA or serum
Muñoz et al., Biochem Biophys Res Commun 2009
(Cardiomegaly) :
IGF-1 stimulated MEF2 dependent-gene transcription in a time dependent manner, as indicated by increased MEF2 promoter-driven reporter gene activity ;
IGF-1 also
induced p38-MAPK phosphorylation, while an inhibitor of
p38-MAPK decreased both effects
Hutchison et al., Mol Endocrinol 2012
(MAP Kinase Signaling System) :
Moreover,
IGF-I , which stimulates proliferation,
suppresses p38 activation