◀ Back to AKT1S1

AKT1S1 — ULK1

Text-mined interactions from Literome

Dunlop et al., Autophagy 2011 : ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding ... We propose a new mechanism whereby ULK1 contributes to mTORC1 inhibition through hindrance of substrate docking to Raptor
Jung et al., Autophagy 2011 : These results demonstrate that ULK1 negatively regulates the kinase activity of mTORC1 and cell proliferation in a manner independent of Atg5 and TSC2