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PRKCB — RELA
Text-mined interactions from Literome
Saijo et al., J Exp Med 2002
:
Using mice deficient for protein kinase C beta (PKCbeta) we show an essential
role of
PKCbeta in the phosphorylation of IKKalpha and the subsequent activation of
NF-kappaB in B cells
Su et al., Nat Immunol 2002
(Lymphoma, B-Cell) :
PKC-beta controls
I kappa B kinase lipid raft recruitment and activation in response to BCR signaling ... Here, we demonstrate that
PKC-beta is specifically
required for B cell receptor (BCR) mediated
NF-kappa B activation
Antony et al., Exp Cell Res 2003
(Calcium Signaling) :
Pharmacological inhibition of PKC isozymes and Ras revealed that the BCR induced activation of
NF-kappaB requires conventional
PKCbeta , whereas that of NFAT may involve non-conventional PKCdelta and Ras pathways
Banan et al., Am J Physiol Cell Physiol 2004
:
We hypothesized that EGF induced activation of
PKC-beta1 prevents oxidant
induced activation of
NF-kappaB and the consequences of NF-kappaB activation, F-actin, and barrier dysfunction
Guo et al., Curr Opin Immunol 2004
:
Recent evidence indicates that
PKCbeta might
regulate inhibitor of kappaB kinase (IKK) and
NF-kappaB activation through interaction with the CARMA1/Bcl10/MALT signaling complex in BCR microdomains
Shah et al., Eur J Cancer Prev 2006
(Colorectal Neoplasms) :
Chronic c-9,t-11-CLA and t-10, c-12-CLA treatment inhibited DCA induced
PKC beta1 and PKC delta translocation and also
inhibited NF-kappaB activation