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AR — TP53

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: Complex of AR-AR → TP53 (directlyDecreases, AR/AR Activity) Shenk et al., J Biol Chem 2001*
  Evidence: p53 appears to exert its inhibition of human AR by disrupting its amino- to carboxyl-terminal (N-to-C) interaction, which is thought to be responsible for the homodimerization of this receptor

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: AR — TP53 (physical association, two hybrid) Kang et al., FEBS Lett 2009*

Text-mined interactions from Literome

Alimirah et al., Neoplasia (New York, N.Y.) 2007 (Adenocarcinoma...) : Expression of androgen receptor is negatively regulated by p53
Tan et al., Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2012 : Anacardic acid ( 6-pentadecylsalicylic acid ) induces apoptosis of prostate cancer cells through inhibition of androgen receptor and activation of p53 signaling