Zhu et al., Oncogene 2012
(Colonic Neoplasms...) :
Corroborating these results, PAK1 is required for full Wnt signaling, and superactivation of ß-catenin is achieved by simultaneous knockdown of adenomatous polyposis coli protein and activation of PAK1 Khare et al., Biochem Pharmacol 2013
(Colonic Neoplasms...) :
Our data demonstrates novel pharmacological mechanism of mesalamine in modulation of cell adhesion and role of PAK1 in APC ( min ) polyposis