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CA2 — ITGA2B

Text-mined interactions from Literome

van Vliet et al., Br J Haematol 1986 (Telangiectasia, Hereditary Hemorrhagic...) : Evidence is presented that the antigenic binding site on GP IIb is made accessible to the antibody by means of the effect of EDTA on the Ca2+ dependent GP IIb/IIIa complex
Fitzgerald et al., J Biol Chem 1985 : Platelet membrane glycoproteins (GP) IIb and IIIa form a Ca2+ dependent , heterodimer complex ( GP IIb-IIIa ) in detergent solution
Fitzgerald et al., J Biol Chem 1987 : Platelet membrane glycoprotein (GP) IIIa forms a Ca2+ dependent heterodimer complex with GP IIb
Varon et al., Proc Natl Acad Sci U S A 1983 (Autoimmune Diseases...) : 3B2 reacted with the GPIIb-GPIIIa-Ca2+ complex in the presence of excess Ca2+ and with GPIIb alone in the presence of excess EGTA
Ikeda et al., Thromb Haemost 1993 (Thrombasthenia) : The increase in [Ca2+ ] i may act as an intracellular message and cause the activation of GP IIb-IIIa ; the latter receptor then binds vWF and mediates irreversible aggregation
Mazzucato et al., Thromb Haemost 1996 (Second Messenger Systems) : The increase in [Ca2+ ] i may act as an intracellular message and cause the activation of the GP IIb-IIIa complex
Phillips et al., Circulation 1997 : Effect of Ca2+ on GP IIb-IIIa interactions with integrilin : enhanced GP IIb-IIIa binding and inhibition of platelet aggregation by reductions in the concentration of ionized calcium in plasma anticoagulated with citrate