Gene interactions and pathways from curated databases and text-mining

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APEX1 — CD40

Text-mined interactions from Literome

Merluzzi et al., J Biol Chem 2004 : In this study we demonstrate that the redox factor APE/Ref-1 acts as a key signaling intermediate in response to CD40 mediated B cell activation
Merluzzi et al., Mol Immunol 2008 : Here we show that TRAF2 is involved in CD40 mediated induction of APE/Ref-1 nuclear translocation and that the two proteins physically interact in vitro and in vivo