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CCR7 — CD40

Text-mined interactions from Literome

Onaitis et al., Surg Oncol Clin N Am 2002 (Neoplasms) : A number of studies have demonstrated that maturation signals such as inflammatory cytokines and CD40 ligation lead to down-regulation of antigen processing and up-regulation of the chemokine receptor CCR7 , which leads to homing to lymph nodes [ 46 ] as well as the MHC molecules, costimulatory molecules, and maturation markers [ 8,47,48 ]
D'Amico et al., Blood 2004 (Precursor Cell Lymphoblastic Leukemia-Lymphoma) : Engaging CD40 induced the up-regulation of CCR7 in 7 of 11 patients and then the migration to CCL19 in 2 of 5 patients