Gene interactions and pathways from curated databases and text-mining

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GRP — SCT

Text-mined interactions from Literome

Gower et al., Gastroenterology 1990 (Gastrinoma...) : Somatostatin 14 inhibited secretin , bombesin, and gastrin releasing peptide stimulated gastrin release but did not alter basal release
Korman et al., Cancer Res 1986 (Carcinoma, Small Cell...) : Secretin/vasoactive intestinal peptide stimulated secretion of bombesin/gastrin releasing peptide from human small cell carcinoma of the lung
Glad et al., Scand J Gastroenterol 1994 : The effect of gastrin releasing peptide on porcine pancreaticobiliary bicarbonate secretion is mediated by secretin
Glad et al., Scand J Gastroenterol 1996 (Disease Models, Animal) : Intravenous infusion of the GRP antagonist BIM-26226 completely abolished the GRP induced secretin release and pancreatic and hepatic bicarbonate secretion ... Thus, we conclude that GRP likely plays an insignificant role in a possible peptidergic regulation of acid induced intestinal secretin release and that GRP has no regulatory function in acid induced pancreaticobiliary bicarbonate secretion
Chang et al., Am J Physiol 1998 : Secretin release from both cell types was stimulated by various agents known to elicit secretin release and by the neuropeptides BB, GRP , and PACAP, suggesting a comparable response between the two cell preparations ... BB, GRP , and PACAP stimulated secretin release time and concentration dependently