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BMX — PI3

Text-mined interactions from Literome

Ekman et al., Oncogene 2000 : Activation of Bmx required phosphatidylinositol 3-kinase (PI-3K) as demonstrated by the ability of PI-3K inhibitors to block the activation signal
Jiang et al., J Biol Chem 2007 (Prostatic Neoplasms) : We found that the nonreceptor Tec family tyrosine kinase Bmx/Etk was activated by tyrosine phosphorylation downstream of Src and PI 3-kinase in PTEN-deficient LNCaP and PC3 PCa cells and that Bmx down-regulation by short interfering RNA markedly inhibited LNCaP cell growth ... Bmx stimulation in response to heregulin-beta1 and EGF was Src dependent, and heregulin-beta1 stimulation of Bmx was also PI 3-kinase dependent