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PREX2 — RAC1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Rosenfeldt et al., FEBS Lett 2004
:
P-REX2 promoted increased levels of GTP bound
Rac that could be further stimulated by enhancing PI-3K activity
Li et al., Prostaglandins Other Lipid Mediat 2005
:
Role of guanine nucleotide exchange factor
P-Rex-2b in sphingosine 1-phosphate induced
Rac1 activation and cell migration in endothelial cells ... Furthermore, we found that
P-Rex2b is
involved in S1P induced
Rac1 activation and cell migration in ECs because siRNA mediated suppression of P-Rex2b expression in ECs diminished Rac1 activation and cell migration in response to S1P