Slim et al., Toxicological sciences : an official journal of the Society of Toxicology 1999
:
Furthermore, PCB mediated induction of NF-kappaB and production of IL-6 were only partially blocked by alpha-NF
Kwon et al., Biol Pharm Bull 2002
(Inflammation) :
TNF-alpha and IL-1beta expressed their respective mRNA in the presence or absence of PCB, while cyclooxygenase-2 (COX-2) and IL-6 mRNA expression were highly induced by PCB after 2 h ... Moreover, pre-treatment with the nuclear factor (NF)-kappaB pathway inhibitor, pyrrolidine dithiocarbamate, suppressed COX-2, TNF-alpha and IL-1beta induction and reduced the IL-6 mRNA levels induced by PCB