UCSC Genome Browser Gene Interaction Graph

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Gene interactions and pathways from curated databases and text-mining

◀ Back to ADAM17

ADAM17 — BDNF

Pathways - manually collected, often from reviews:

NCI Pathway Database p75(NTR)-mediated signaling: TACE (ADAM17) → proBDNF (dimer)/p75(NTR)/Sortilin/TRAF6/NRIF complex (NGFR-BDNF-SORT1-TRAF6-ZNF274) (modification, activates)
Weskamp et al., J Biol Chem 2004
Evidence: mutant phenotype, other species