Shirakabe et al., Genes Cells 2001
(Craniosynostoses) :
These results suggest that regulation of the activity of Runx2 by Msx2 and Dlx5 plays an important role in the mammalian skull development
Hassan et al., J Biol Chem 2006
:
Our studies further show regulation of the Runx2 gene by several homeodomain proteins : MSX2 and CDP/cut repress whereas DLX3 and DLX5 activate endogenous Runx2 expression and promoter activity in non-osseous cells and osteoblasts