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RUNX1 — RUNX2

Text-mined interactions from Literome

Otto et al., J Cell Biochem 2003 : While Runx1 is essential for mature haematopoiesis and Runx2 for osteochondrogenesis, Runx3 has a function in the nervous system
Jin et al., J Biol Chem 2004 : Genetic analyses of animals and humans have revealed the involvement of RUNX1 in hematopoiesis and leukemia, RUNX2 in osteogenesis and cleidocranial dysplasia, and RUNX3 in the development of T-cells and dorsal root ganglion neurons and in the genesis of gastric cancer
Yamashiro et al., J Bone Miner Res 2004 : We evaluated the detailed expression patterns of Runx1 and Sox9 in various types of bone formation, and determined whether Runx1 expression was affected by Runx2 deficiency and Runx2 expression by Runx1 deficiency ... Runx2 expression was not affected by gene disruption of Runx1 , whereas the expression domains of Runx1 were extended in Runx2 ( -/- ) mice compared with wildtype mice
Wang et al., J Bone Miner Res 2005 : Knockdown or Runx1 potently inhibits type II collagen, alkaline phosphatase, and Runx2 and has a late inhibitory effect on type X collagen
Shen et al., J Biol Chem 2005 : This enhancement was inhibited by AML-1/ETO , an inhibitor of Runx2
Park et al., Mol Cell Endocrinol 2012 : Together, these novel findings provide support for the role of RUNX2 in down-regulation of Runx1 , Ptgs2, and Tnfaip6 during the late ovulatory period to support proper ovulation and/or luteinization