Gene interactions and pathways from curated databases and text-mining

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ADAM10 — IL8

Text-mined interactions from Literome

Lee et al., Arterioscler Thromb Vasc Biol 2012 (Atherosclerosis) : Free thiol cysteine analogs showed inhibition of IL-8 induction by Ox-PAPC, and both a cysteine analog and a cell surface thiol blocker strongly inhibited ADAM activity induction by Ox-PAPC
Breshears et al., J Biol Chem 2012 : Both ADAM10 and ADAM17 contribute to SDC1 shedding and IL-8 production by HVECs in response to TSST-1