Cheon et al., Biochem Biophys Res Commun 2008
:
As a result, inhibition of SPHK by SKI blocked phosphorylation of p38 MAPK , showing that SPHK activation by IL-18 is an upstream signal of p38 MAPK activation
Prakash et al., PloS one 2010
(Mycobacterium Infections, Nontuberculous) :
In addition, our results also unraveled a novel regulation of p38MAPK by SphK-1 during M. smegmatis infection and generation of NO in macrophages