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CD40 — IL1A
Text-mined interactions from Literome
von Leoprechting et al., Cancer Res 1999
(Melanoma) :
CD40 expression could be
enhanced in CD40 positive MM by stimulation with IFN-gamma and tumor necrosis factor-alpha but not by
interleukin (IL)-1beta or CD40 triggering
Bergamini et al., J Infect Dis 2000
(HIV Infections) :
The effect of HIV-1 infection on recombinant
CD40 ligand (CD40L) induced
interleukin (IL)-1beta and IL-6 production by human macrophages was analyzed
Galy et al., J Immunol 1992
:
IL-1 alpha , TNF-alpha, IFN-gamma, but not IL-4, significantly
up-regulated the membrane expression of
CD40 on cultured TEC
Burger et al., J Immunol 2004
:
CD40LT induced neither transcript nor protein of cytokines in monocytes, whereas in IFN-gamma-macrophages,
IL-1beta and TNF mRNA were observed, but only TNF was measured in cell supernatants
Mutamba et al., Eur J Immunol 2012
:
Furthermore,
IL-1F8 stimulated increased
CD40 and CD80 expression and IL-18 and IL-12 p70 production by MDDCs, which induced proliferation of IFN-? producing CD3 ( + ) lymphocytes ( indicative of inflammatory Th1 subsets )
Burdin et al., J Immunol 1995
:
First, both
CD40 and Ag receptor ( AgR ) cross linking
induced purified tonsillar human B lymphocytes to secrete the same pattern of cytokines, including IL-1 beta, IL-6, IL-10, granulocyte-macrophage-CSF, and TNF-alpha, whereas
IL-1 alpha , IL-2, IL-3, IL-4, IL-5, IL-7, granulocyte (G)-CSF, or IFN-gamma were not detected
Shattuck et al., Mol Cell Biol 1994
(Melanoma) :
The effect of deletion or mutation of the MGSA/GRO alpha NF-kappa B element, combined with data from gel mobility shift analyses, indicates that the NF-kappa
B p50/p65 heterodimer in RPE cells
plays an important role in
IL-1- and TNF alpha enhanced gene transcription
McLellan et al., Eur J Immunol 1996
:
However,
CD40 was rapidly up-regulated by culture, and its expression was further
enhanced by
interleukin (IL)-1 alpha , IL-1 beta, IL-3, tumor necrosis factor-alpha and granulocyte/macrophage-colony stimulating factor
Metcalfe et al., J Clin Endocrinol Metab 1998
:
CD40 expression was
up-regulated by
interleukin-1alpha and interferon-gamma, but not by TSH
Jakob et al., J Immunol 1998
:
Flow cytometry of FSDDC-A revealed that
IL-1 , TNF-alpha, and LPS
induced increased expression of MHC class II,
CD40 , and CD86 and decreased E-cadherin expression that was temporally related to dissociation of aggregates
Suo et al., Brain Res 1998
(Alzheimer Disease...) :
Moreover,
IL-1beta and IFN-gamma synergistically
increased the Abeta induced expression of
CD40 and IFN-gammaR