Gene interactions and pathways from curated databases and text-mining

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CD40 — IL1A

Text-mined interactions from Literome

von Leoprechting et al., Cancer Res 1999 (Melanoma) : CD40 expression could be enhanced in CD40 positive MM by stimulation with IFN-gamma and tumor necrosis factor-alpha but not by interleukin (IL)-1beta or CD40 triggering
Bergamini et al., J Infect Dis 2000 (HIV Infections) : The effect of HIV-1 infection on recombinant CD40 ligand (CD40L) induced interleukin (IL)-1beta and IL-6 production by human macrophages was analyzed
Galy et al., J Immunol 1992 : IL-1 alpha , TNF-alpha, IFN-gamma, but not IL-4, significantly up-regulated the membrane expression of CD40 on cultured TEC
Burger et al., J Immunol 2004 : CD40LT induced neither transcript nor protein of cytokines in monocytes, whereas in IFN-gamma-macrophages, IL-1beta and TNF mRNA were observed, but only TNF was measured in cell supernatants
Mutamba et al., Eur J Immunol 2012 : Furthermore, IL-1F8 stimulated increased CD40 and CD80 expression and IL-18 and IL-12 p70 production by MDDCs, which induced proliferation of IFN-? producing CD3 ( + ) lymphocytes ( indicative of inflammatory Th1 subsets )
Burdin et al., J Immunol 1995 : First, both CD40 and Ag receptor ( AgR ) cross linking induced purified tonsillar human B lymphocytes to secrete the same pattern of cytokines, including IL-1 beta, IL-6, IL-10, granulocyte-macrophage-CSF, and TNF-alpha, whereas IL-1 alpha , IL-2, IL-3, IL-4, IL-5, IL-7, granulocyte (G)-CSF, or IFN-gamma were not detected
Shattuck et al., Mol Cell Biol 1994 (Melanoma) : The effect of deletion or mutation of the MGSA/GRO alpha NF-kappa B element, combined with data from gel mobility shift analyses, indicates that the NF-kappa B p50/p65 heterodimer in RPE cells plays an important role in IL-1- and TNF alpha enhanced gene transcription
McLellan et al., Eur J Immunol 1996 : However, CD40 was rapidly up-regulated by culture, and its expression was further enhanced by interleukin (IL)-1 alpha , IL-1 beta, IL-3, tumor necrosis factor-alpha and granulocyte/macrophage-colony stimulating factor
Metcalfe et al., J Clin Endocrinol Metab 1998 : CD40 expression was up-regulated by interleukin-1alpha and interferon-gamma, but not by TSH
Jakob et al., J Immunol 1998 : Flow cytometry of FSDDC-A revealed that IL-1 , TNF-alpha, and LPS induced increased expression of MHC class II, CD40 , and CD86 and decreased E-cadherin expression that was temporally related to dissociation of aggregates
Suo et al., Brain Res 1998 (Alzheimer Disease...) : Moreover, IL-1beta and IFN-gamma synergistically increased the Abeta induced expression of CD40 and IFN-gammaR