Gene interactions and pathways from curated databases and text-mining

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IL1A — PTH

Text-mined interactions from Literome

Yamashita et al., J Cell Physiol 1990 : Parathyroid hormone (PTH) increased cAMP production in KS-4 cells, and PTH and interleukin-1 alpha also induced TRACP positive MNCs in co-cultures with spleen cells
Linkhart et al., J Bone Miner Res 1991 (Bone Resorption) : Previous reports that IL-6 was secreted in murine osteoblast and bone organ cultures in response to IL-1 and PTH suggested that IL-6 has paracrine effects on bone resorption or formation
Nielsen et al., Biochem Biophys Res Commun 1997 : IL-1 might therefore play a role as a auto- and/or paracrine factor in the regulation of the PTH secretion