Gene interactions and pathways from curated databases and text-mining

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IL1A — TAB2

Text-mined interactions from Literome

Takaesu et al., Mol Cell 2000 : Expression of TAB2 induces JNK and NF-kappaB activation, whereas a dominant negative mutant TAB2 impairs their activation by IL-1 ... IL-1 stimulates translocation of TAB2 from the membrane to the cytosol where it mediates the IL-1 dependent association of TAK1 with TRAF6
Takaesu et al., Mol Cell Biol 2001 (MAP Kinase Signaling System) : We show that IL-1 stimulation induces the rapid but transient association of IRAK, TRAF6, TAB2 , and TAK1 ... We show that IL-1 stimulation induces the rapid but transient association of IRAK, TRAF6, TAB2 , and TAK1
Qian et al., J Biol Chem 2001 : The membrane bound IRAK similarly mediates the IL-1 induced translocation of TAB2 from the membrane to the cytosol ... Our results show that IRAK is required for the IL-1 induced phosphorylation of TAK1, TAB1 , and TAB2