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CISH — IRS1

Text-mined interactions from Literome

Shi et al., Diabetes 2006 (Insulin Resistance) : In adipocytes, suppressor of cytokine signaling (SOCS)3 deficiency increases insulin stimulated insulin receptor substrate (IRS)-1 and -2 phosphorylation, IRS associated phosphatidylinositol 3 kinase activity, and insulin stimulated glucose uptake ... Moreover, SOCS3 is required for tumor necrosis factor-alpha full inhibition of insulin stimulated IRS-1 and -2 phosphorylation, phosphatidylinositol 3 kinase activity, and glucose uptake
Ishizuka et al., Endocrinology 2007 (Insulin Resistance) : Chronic tumor necrosis factor-alpha treatment causes insulin resistance via insulin receptor substrate-1 serine phosphorylation and suppressor of cytokine signaling-3 induction in 3T3-L1 adipocytes