Gene interactions and pathways from curated databases and text-mining

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NOS2 — PTBP1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Pautz et al., J Biol Chem 2006 (Carcinoma...) : The polypyrimidine tract binding protein ( PTB ) is involved in the post-transcriptional regulation of human inducible nitric oxide synthase expression ... The polypyrimidine tract binding protein ( PTB ) is involved in the post-transcriptional regulation of human inducible nitric oxide synthase expression ... Therefore we analyzed the involvement of PTB in human iNOS expression ... Overexpression of PTB resulted in enhanced cytokine induced iNOS expression ... Transfection experiments showed that PTB mediates its effect on iNOS expression via binding to this region
Montcalm-Smith et al., Aviat Space Environ Med 2007 (Decompression Sickness...) : HO-1 and HSP-70 increased in the brain, and HO-1, Egr-1, and iNOS increased in the lungs of animals with DCS
Nam et al., PloS one 2009 (Inflammation) : A mathematical model developed to understand the complex dynamics of the system predicts two thresholds in the magnitudes of DCS, one for the inhibition of IL-1beta induced expression of NOS2 by DCS at low magnitudes, and second for the DCS induced expression of NOS2 at higher magnitudes