Natarajan et al., J Immunol 2001
(Second Messenger Systems) :
Whereas B cell Ag receptor (BCR) cross linking alone stimulated increased expression of CD86 , up-regulation of CD80 required dual stimulation with anti-IgM and anti-CD54
Chung et al., Int Immunol 2002
:
However, both CD23 ( - ) and CD23 ( + ) transitional B cells failed to up-regulate CD86 ( B7-2 ) in response to BCR ligation
Mongini et al., Cell Immunol 2002
:
In the presence of IL-4, BCR : CD21 co-ligation augmented CD86 and CD80 expression under conditions of greater BCR engagement
Marshall-Clarke et al., Immunology 2003
:
We show that activity of the enzyme phosphatidylinositol 3-kinase is critical for MHC II hyperexpression and induction of CD86 in response to ligation of the BCR or CD38, but not for responses to other stimuli including interleukin-4, lipopolysaccharide and CD40 ligation