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PLK1 — UBE2D1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Liu et al., Proc Natl Acad Sci U S A 2002
:
Plks have been reported to mediate multiple mitotic processes, including bipolar spindle formation, activation of Cdc25C, actin ring formation,
centrosome maturation, and
activation of the
anaphase promoting complex
van Vugt et al., J Biol Chem 2004
:
These data indicate that activation of the
anaphase promoting complex or cyclosome ( APC/C ) -Cdc20 complex that is under control of the spindle assembly checkpoint does not
require Plk1 activity
Hansen et al., Mol Biol Cell 2004
:
Plk1 regulates activation of the
anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP dependent destruction of the APC Inhibitor Emi1
Kotani et al., Mol Cell 1998
:
PKA and MPF activated
polo-like kinase regulate
anaphase promoting complex activity and mitosis progression