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MSK38 — TP53

Text-mined interactions from Literome

Llanos et al., Science signaling 2009 (MAP Kinase Signaling System) : MSK2 inhibits p53 activity in the absence of stress ... Mitogen- and stress activated kinase 2 ( MSK2 ) inhibits the transcription factor p53 , and we investigate here the mechanisms underlying this inhibition
Gesser et al., Inflamm Res 2011 (Psoriasis) : Dimethylfumarate inhibits MIF induced proliferation of keratinocytes by inhibiting MSK1 and RSK1 activation and by inducing nuclear p-c-Jun ( S63 ) and p-p53 ( S15 ) expression ... Our results indicate that the specific inhibitory effects of DMF on RSK1 and MSK1 activation together with the induction of p-c-Jun ( S63 ) and p-p53 ( S15 ) lead to the inhibition of keratinocyte proliferation, partly explaining the anti-psoriatic effect of DMF