Gene interactions and pathways from curated databases and text-mining

◀ Back to PDGFRB

FN1 — PDGFRB

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: PDGFRB → Complex of FN1-ITGAV-ITGB3 (increases, FN1/ITGAV/ITGB3 Activity)
    Borges et al., J Biol Chem 2000
    Evidence: The integrin-RTK cooperation may make it possible for cell attachment to induce an RTK response independently of the growth factor ligand. Cells that attach to fibronectin (a ligand of avb3) show autophosphorylation of PDGF-Rb (6) and relocation of the receptor to focal contacts