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CD80 — IL10

Text-mined interactions from Literome

Liu et al., Scand J Immunol 1999 (Lupus Erythematosus, Systemic) : The effects of interleukin-10 (IL-10) on the expression of CD80 and CD86 on monocytes from patients with SLE and normal controls were similar
Kooy et al., J Pathol 1999 (Carcinoma, Basal Cell...) : Interferon-gamma induced ICAM-1 and CD40 expression, complete lack of HLA-DR and CD80 ( B7.1 ), and inconsistent HLA-ABC expression in basal cell carcinoma : a possible role for interleukin-10 ? ... It may be concluded that it is highly likely that the presence of IL-10 in BCC is directly or indirectly responsible for the complete lack of expression of HLA-DR, ICAM-1, CD40 and CD80 and the inconsistent expression of HLA-ABC on BCC cells in situ and may be a way of escaping immune survillance
Wang et al., Acta Pharmacol Sin 2001 : To study the effects of Tripterygium wilfordii ( TII ) and IL-10 on human leukocyte antigen-DR ( HLA-DR ) and CD80 expressions and IL-12 p40 subunit production and transcription of dendritic cells ( DC ) in human peripheral blood from healthy volunteers in vitro
Janssen et al., Am J Respir Cell Mol Biol 2002 (Asthma...) : This IL-10 production by the OVA-Mphi was dependent on MHC-TCR and CD86-CD28, but not CD80-CD28 or CD40-CD154 interactions
Salek-Ardakani et al., Virology 2002 : Viral IL-10 in a concentration dependent manner inhibited both basal- and IFN-gamma induced HLA-class II, ICAM-1 ( basal levels of ICAM-2 and ICAM-3 is unaffected ), CD80 , and CD86 up-regulation when added simultaneously with IFN-gamma
Blanchet et al., Am J Respir Crit Care Med 2004 (Alveolitis, Extrinsic Allergic) : To test the effect of nicotine on alveolar macrophages, AMJ2-C11 cells were treated with nicotine and stimulated with lipopolysaccharide or Saccharopolyspora rectivirgula, a causative agent of HP. Nicotine reduced tumor necrosis factor release and tumor necrosis factor, interleukin-10 , and IFN-gamma mRNA expression after stimulation and decreased CD80 expression by 55 % in lipopolysaccharide stimulated cells and by 41 % in S. rectivirgula stimulated cells ... To test the effect of nicotine on alveolar macrophages, AMJ2-C11 cells were treated with nicotine and stimulated with lipopolysaccharide or Saccharopolyspora rectivirgula, a causative agent of HP. Nicotine reduced tumor necrosis factor release and tumor necrosis factor, interleukin-10 , and IFN-gamma mRNA expression after stimulation and decreased CD80 expression by 55 % in lipopolysaccharide stimulated cells and by 41 % in S. rectivirgula stimulated cells
Balkhi et al., J Leukoc Biol 2004 : Further analyses showed that stimulation with anti-CD80 increased interleukin (IL)-10 and transforming growth factor-beta-1 levels with a concomitant reduction in IL-12p40 and interferon-gamma levels from BMDCs and CD11c ( + ) /CD8a ( - ) DCs and to a lesser extent, from CD11c ( + ) /CD8a ( + ) DCs
Gutzmer et al., Immunology 2004 : After up-regulation of the C3aR by IFN-alpha+ IFN-gamma, C3a significantly up-regulated the surface expression of CD54, CD83 and CD86, but not of CD40, CD80 or human leucocyte antigen ( HLA ) -DR. C3a had no effect on the production of interleukin (IL)-10 or IL-12p70, or on the capacity of MoDC to stimulate autologous T-cell proliferation
Steers et al., Vaccine 2008 : L ( LA ) enhanced the surface expression of MHC class I, class II, CD80 , and CD86 molecules, induced the secretion of IFN-gamma, IL-12p40, TNF-alpha and IL-10 , and caused a shift in the proteasome profile from constitutive to immunoproteasomes as observed by the induction of beta2i, beta5i, PA28alpha, and PA28beta subunits
St Paul et al., Vet Immunol Immunopathol 2012 : Furthermore, the results indicated that LPS and poly I:C induced the greatest IFN-? and IL-10 responses, respectively, while CpG ODN was the most efficacious inducer of CD80 and MHC-II expression
Ranheim et al., Cell Immunol 1995 : Tumor necrosis factor-alpha facilitates induction of CD80 ( B7-1 ) and CD54 on human B cells by activated T cells : complex regulation by IL-4, IL-10 , and CD40L
Ozawa et al., Eur J Immunol 1996 : Interferon-gamma and interleukin-10 inhibit antigen presentation by Langerhans cells for T helper type 1 cells by suppressing their CD80 ( B7-1 ) expression ... Based on the recently reported effect of interferon (IFN)-gamma and interleukin (IL-)-10 on the expression of CD80 and CD86 by LC, we examined the effects of these cytokines on the expression of CD54 ( intercellular adhesion molecule-1 ) and CD40 in addition to CD80 and CD86 on LC, and correlated the expression of each co-stimulatory molecule with antigen presentation for a Th1 clone by cultured LC (cLC) treated with these cytokines ... As previously reported, IL-10 or IFN-gamma inhibited the up-regulation of CD80 expression
Romano et al., J Immunol 1996 : Therefore, the NF-kappa B/Rel inhibition might be ascribed to a lack of cooperation between accessory cells and T lymphocytes, resulting from down-regulation of a costimulatory molecule, such as CD80 , produced by IL-10 on activated monocytes
Saito et al., Eur J Immunol 1996 (Acute Disease...) : Furthermore, anti-CD80 + 86 mAb preferentially inhibited the production of interferon (IFN)-gamma, but not IL-4 and IL-10 , when cultures were assayed at 21 days
Zhang et al., Cell Immunol 1997 : Both CD80 and CD86 were able to provide costimulation for interferon-gamma and IL-2 synthesis by rhesus CD4+ T cells, but CD80 costimulation also resulted in synthesis of IL-4 and IL-10
Furuie et al., Eur Respir J 1997 (Pulmonary Fibrosis) : The inhibitory effect of interleukin (IL)-10 on the accessory cell function of AMs and the expression of CD80 and CD86 on AMs were also investigated
Hasegawa et al., Int Immunol 1998 : Thus, IL-10 mediated down-regulation of CD80 on B cells was suggested to be involved in the clonal insufficiency in MS Tg mice in vivo
Möttönen et al., Br J Rheumatol 1998 (Arthritis, Rheumatoid) : IL-10 had no effect on the expression of CD80