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Sakuma et al., Prostaglandins 1991 (Asthma...) : E6123 significantly inhibited PAF inhalation induced eosinophil infiltration into the bronchiole and trachea, and bronchial hyperreactivity in guinea pigs after oral administration at 1 and 10 micrograms/kg, respectively
Barthelson et al., J Allergy Clin Immunol 1990 : PAF inhibited IL-1 release at 1 or 10 pM
Okayasu et al., J Lipid Res 1987 : In myo- [ 3H ] inositol prelabeled cells, PAF induced a transient decrease of [ 3H ] phosphatidylinositol-4,5-bis-phosphate ( TPI ) and [ 3H ] phosphatidylinositol-4-phosphate ( DPI ) at 1 min. PAF stimulation of cultured hepatocytes prelabeled with 32Pi induced a transient decrease of [ 32P ] polyphosphoinositides at 20 sec to 1 min. [ 32P ] LPI appeared within 10 sec after stimulation and paralleled the loss of [ 32P ] PI