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NFKB1 — TFF3
Text-mined interactions from Literome
Chen et al., Biochem Biophys Res Commun 2000
:
Here we show that
TFF3 activated
NF-kappaB p50/p65 heterodimer within 1 h in IEC-18 cells ( a nontransformed rat intestinal epithelial cell line ) ... Taken together, these data indicate that ( 1 ) TFF3 is an endogenous gastrointestinal peptide with anti-anoikic property ; ( 2 )
TFF3 activates
NF-kappaB in enterocytes ; and ( 3 ) TFF3 induced resistance to anoikis in intestinal epithelial cells is mediated by a distinct signaling cascade linked to NF-kappaB
Teng et al., Inflammation 2009
(Colitis) :
The main aims of this study is to evaluate
effects of intraperitoneal injection recombinant human
TFF3 on the expression of tumour necrosis factor alpha (TNF-alpha), toll-like receptor 4 ( TLR4 ), and
nuclear factor kappaB (NF-kappaB) in trinitrobenzene sulphonic acid ( TNBS ) induced colitis mice