Gene interactions and pathways from curated databases and text-mining

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CCNB1 — FOXO1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: FOXO1 → Complex of CCNB1-CDK1 (decreases, CCNB1/CDK1 Activity) Liu et al., Oncogene 2008*
    Evidence: forced expression of FOXO1 causes a delay in the transition from G2 to M phase. This effect is blocked completely by overexpression of CDK1 and cyclin B1.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *