Yoshizaki et al., J Biol Chem 2004
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Moreover, the involvement of MgcRacGAP/CYK-4 in this suppression of Rac1 during cytokinesis was shown by the use of a dominant negative mutant
Bastos et al., J Cell Biol 2012
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We demonstrate that the MKlp1-CYK4 centralspindlin complex is a guanosine triphosphatase activating protein ( GAP ) for Rac1 and not RhoA and that CYK4 negatively regulated Rac1 activity at the cell equator in anaphase