◀ Back to CD4
CD4 — JAG1
Text-mined interactions from Literome
Gramaglia et al., J Immunol 2000
:
The costimulatory receptor OX40 has recently been shown to be involved in primary
CD4 responses to several defined
Ags
Liu et al., J Immunol 2009
:
Ags characterizing tumors or chronic viral infection are generally presented to the host immune system before specific immunotherapy is initiated, and consequent generation of regulatory
CD4 ( + ) T cells can
inhibit induction of desired effector CD8 T cell responses
Ndhlovu et al., J Immunol 2011
:
Additionally, mosaic
Ags induced HIV-specific
CD4 T cell responses
Coursey et al., J Immunol 2011
(Neoplasms, Experimental) :
Furthermore, s.c. tumor rejection requires IL-17, which is produced by IFN-?-deficient
CD4 ( + ) T cells in
response to tumor
Ags ( TAs )
Commandeur et al., J Immunol 2013
(Disease Models, Animal...) :
Finally, IVE-TB
Ags induced strong IFN-? ( + ) /TNF-a ( + ) CD8 ( + ) and TNF-a ( + ) /IL-2 ( + ) CD154 ( + )
/CD4 ( + ) T cell responses in PBMC from long-term latently M. tuberculosis infected individuals
Theodore et al., J Immunol 1996
:
CD4 participation in TCR/CD3 associated activation through interaction with the MHC class II
Ags results in formation of a
CD4-TCR/CD3 complex capable of maximal signal transduction
Andrews et al., J Immunol 1997
(Murine Acquired Immunodeficiency Syndrome) :
As the disease progresses, by wk 8 of infection,
CD4 T cell
response to
Ags and mitogens is severely curtailed and the CD4 T cell population becomes anergic