Gene interactions and pathways from curated databases and text-mining

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CD4 — JAG1

Text-mined interactions from Literome

Gramaglia et al., J Immunol 2000 : The costimulatory receptor OX40 has recently been shown to be involved in primary CD4 responses to several defined Ags
Liu et al., J Immunol 2009 : Ags characterizing tumors or chronic viral infection are generally presented to the host immune system before specific immunotherapy is initiated, and consequent generation of regulatory CD4 ( + ) T cells can inhibit induction of desired effector CD8 T cell responses
Ndhlovu et al., J Immunol 2011 : Additionally, mosaic Ags induced HIV-specific CD4 T cell responses
Coursey et al., J Immunol 2011 (Neoplasms, Experimental) : Furthermore, s.c. tumor rejection requires IL-17, which is produced by IFN-?-deficient CD4 ( + ) T cells in response to tumor Ags ( TAs )
Commandeur et al., J Immunol 2013 (Disease Models, Animal...) : Finally, IVE-TB Ags induced strong IFN-? ( + ) /TNF-a ( + ) CD8 ( + ) and TNF-a ( + ) /IL-2 ( + ) CD154 ( + ) /CD4 ( + ) T cell responses in PBMC from long-term latently M. tuberculosis infected individuals
Theodore et al., J Immunol 1996 : CD4 participation in TCR/CD3 associated activation through interaction with the MHC class II Ags results in formation of a CD4-TCR/CD3 complex capable of maximal signal transduction
Andrews et al., J Immunol 1997 (Murine Acquired Immunodeficiency Syndrome) : As the disease progresses, by wk 8 of infection, CD4 T cell response to Ags and mitogens is severely curtailed and the CD4 T cell population becomes anergic