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EGF — LGALS1

Text-mined interactions from Literome

Maruo et al., J Clin Endocrinol Metab 1992 : Instead, in early placental explant culture EGF stimulated hCG and hPL secretion with a lag period of 72 h, whereas very early placental explants did not respond to EGF with increase in hCG and hPL secretion
Bhaumick et al., J Clin Endocrinol Metab 1992 : Measurement of hPL in the medium revealed that the stimulatory effect ( P less than 0.05 ) of EGF on hPL secretion by total placental cells was proportional to the stimulatory effect of EGF on cell differentiation, as revealed by the obliteration of its stimulatory effect on hPL by BhCG positive cells ... The augmented stimulatory effect of EGF on hPL secretion by all cells in the presence of IGF-I was decreased ( P less than 0.05 ) when expressed per number of human chorionic gonadotropin ( BhCG ) -positive cells
Aoki et al., Nihon Sanka Fujinka Gakkai Zasshi 1991 : EGF stimulated only hPL , hCG production and in contrast, PDGF stimulated 3H-thymidine uptake only
Morrish et al., Endocrinology 1991 : EGF alone induced fractional ( EGF/control ) increases in hCG and hPL release of 2.46 and 2.68, respectively
Maruo et al., J Clin Endocrinol Metab 1987 : The effects of epidermal growth factor (EGF) on the production and secretion of hCG and human placental lactogen (hPL) by cultured placental tissues were investigated in relation to immunohistochemical measurements of cellular EGF receptor levels in the placenta ... This EGF stimulated hCG, hCG alpha, and hPL release was markedly inhibited by concomitant treatment with processing inhibitors ... By contrast, in term placental tissues EGF stimulated only hCG alpha and hPL release, with a lag period of approximately 3 days ... These results demonstrate that EGF , via its receptors on the syncytiotrophoblasts, stimulates the release of both hCG and hPL in normal early placenta
Morrish et al., J Clin Endocrinol Metab 1987 : EGF induced large sustained increases in hCG and human placental lactogen (hPL) secretion in a dose dependent manner
Matsuo et al., Nihon Sanka Fujinka Gakkai Zasshi 1993 : In 4-5 week placenta, EGF and EGF receptor were found to be almost exclusively localized in cytotrophoblasts and EGF enhanced the proliferation of cytotrophoblasts without affecting the ability to secrete hCG and hPL, whereas in 6-12 week placenta, EGF and EGF receptor were predominantly localized in syncytiotrophoblasts and EGF stimulated the secretion of hCG and hPL without affecting the proliferation of cytotrophoblasts
Mochizuki et al., Int J Gynaecol Obstet 1998 (Choriocarcinoma...) : By contrast, in 6-12 week placentas, EGF and EGF receptor were predominantly localized in S-cells, and EGF stimulated hCG and hPL secretion without affecting the proliferative activity of C-cess